alexa Effect of 17 a-Methyl Testosterone on Haematology and Histology of Liver and Heart of Oreochromis andersonii (Castelnau, 1861)
ISSN: 2155-9910

Journal of Marine Science: Research & Development
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Effect of 17 a-Methyl Testosterone on Haematology and Histology of Liver and Heart of Oreochromis andersonii (Castelnau, 1861)

Kefi AS1*, Kang’ombe J11, Kassam D1 and Katongo C2

1Lilongwe University of Agriculture and Natural Resources, Bunda Campus, P.O. Box 219, Lilongwe, Malawi

2University of Zambia, Department of Biological Sciences, P. O. Box 32379, Lusaka, Zambia

Corresponding Author:
Kefi AS
Lilongwe University of Agriculture and Natural Resources
Bunda Campus, P.O. Box 219, Lilongwe, Malawi
E-mail: [email protected]

Received Date: August 02, 2013; Accepted Date: August 27, 2013; Published Date: August 30, 2013

Citation: Kefi AS, Kang’ombe J, Kassam D, Katongo C (2013) Effect of 17 α-Methyl Testosterone on Haematology and Histology of Liver and Heart of Oreochromis andersonii (Castelnau, 1861). J Marine Sci Res Dev 3:130. doi: 10.4172/2155-9910.1000130

Copyright: © 2013 Kefi AS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

The aim of the study was to investigate the effect of 17 α-methyl testosterone (MT) on haematology and histology of liver and heart of Oreochromis andersonii subjected to varying levels of MT. Three different doses (40, 60 and 90 mgMT/kg feed) of MT were administered to O. andersonii. Final mean weight (g), gonadosomatic, cardiosomatic and hepatosomatic indices did not differ (P>0.05) among the treatments. Similarly, survival of the O. andersonii in all the treatments did not differ (P>0.05) significantly. Of the haematological and blood chemistry parameters determined, only haemoglobin (Hb), red blood cells (RBC), haematocrit and uric acid were significantly different (P<0.05), among the treatments with the control group having the highest of the latter two parameters. Haemoglobin (r=-0.743; P<0.05) and Red Blood Cells (RBC) (r=-0.726; P<0.05) showed significant association with MT levels. All the treatments did not show any histopathological differences in the liver and heart. However, all the liver samples showed haemosidrein (HE) and extra–hepatic pancreas (EH), while the heart exhibited the vacuolar degeneration (VD). The length–weight relationship coefficient differed (P<0.05) among the treatments with the fish fed with 40 mgMT/kg having the highest slope (2.642), although it only differed (P<0.05) with that of 90 mgMT/kg (1.547), which exhibited the worst condition. The study shows that the oral administration of MT for a short period of up to thirty (30) days does not affect the physiology of O. andersonii. Furthermore, the safety of MT to O. andersonii is, therefore, proved under the conditions of the current experiment. However, there are signs of condition deterioration in high levels of MT.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords