Exercise Training and Insulin Resistance: A Current Review | OMICS International | Abstract
ISSN: 2165-7904

Journal of Obesity & Weight Loss Therapy
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Review Article

Exercise Training and Insulin Resistance: A Current Review

Tyler E Keshel1 and Robert H Coker1,2*
1Institute of Arctic Biology, University of Alaska-Fairbanks, Fairbanks, AK, USA
2Center for Translational Research in Aging and Longevity, Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA
Corresponding Author : Robert H. Coker, Ph.D
Institute for Arctic Biology
University of Alaska-Fairbanks
902 North Koyukuk Drive, Fairbanks, AK, 99775-7000, USA
Tel: 907-474-6701
Fax: 907-474-5700
E-mail: [email protected]
Received: July 14, 2015 Accepted: July 22, 2015 Published: July 30, 2015
Citation: Keshel TE, Coker RH (2015) Exercise Training and Insulin Resistance: A Current Review. J Obes Weight Loss Ther S5:003. doi: 10.4172/2165-7904.S5-003
Copyright: © 2015 Keshel TE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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There is a general perception that increased physical activity will improve glucose homeostasis in all individuals. While this is an attractive concept, this conclusion may be overly simplistic and even misleading. The topic was reviewed extensively over 30 years ago and it was concluded that acute exercise enhances glucose uptake. However, in some cases the chronic influence of interventions utilizing exercise may have little effect on glucose metabolism. Moreover, insulin resistance often returns to near baseline levels within a couple of days following cessation of the exercise bout; leaving the overall effectiveness of the intervention in question. Since improving glucose homeostasis should be the focal endpoint of any intervention designed to mitigate the overwhelming degree of insulin resistance in individuals at risk for metabolic disease, it is essential to evaluate the key components of a successful approach.