alexa Formulation and Evaluation of Fast Dissolving Tablets of Diclofenac Sodium by Novel Hole Technology
ISSN: 2329-9053

Journal of Molecular Pharmaceutics & Organic Process Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Formulation and Evaluation of Fast Dissolving Tablets of Diclofenac Sodium by Novel Hole Technology

Renati Damodar1*, Babji Movva1, Mallikarjun PN1, Chaitanya Pasumarthy2, Nishanth Kona3 and Varsha PV4
1Department of Pharmaceutics, Vignan Institute of Pharmaceutical Technology, Visakhapatnam, Andhra Pradesh, India
2Mother Teresa College of Pharmacy, Ghatkesar, Hyderabad, India
3Department of Pharmaceutics, Sree Siddaganga College Pharmacy, Tumkur, Karnataka, India
4Department of Biotechnology, GITAM University, Visakhapatnam, Andhra Pradesh, India
Corresponding Author : Renati Damodar
Department of Pharmaceutics
Vignan Institute of Pharmaceutical Technology
Visakhapatnam, Andhra Pradesh, India
Tel: +918500932050
E-mail: [email protected]
Received May 27, 2014; Accepted July 28, 2014; Published July 31, 2014
Citation: Damodar R, Movva B, Mallikarjun PN, Pasumarthy C, Kona N, et al. (2014) Formulation and Evaluation of Fast Dissolving Tablets of Diclofenac Sodium by Novel Hole Technology. J Mol Pharm Org Process Res 2:116. doi: 10.4172/2329-9053.1000116
Copyright: © 2014 Damodar R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related article at
DownloadPubmed DownloadScholar Google
 

Abstract

Research has done to prepare Diclofenac Sodium quick dissolving tablets by Hole technology. Once these quick dissolving tablets contact with gastro enteric fluids, the fluid can enter the hole within the tablet and immediate breaking of the tablet goes to take place. This quick disintegration of tablets is additionally influenced by the formation of latest absolute space. The ready FDTs were subjected to numerous pre and post formulation studies. Its disintegration and dissolution rates were compared with the management formulation (without hole). In-vitro drug release of FDTs (DH6) showed virtually 100.92% of the drug was discharged at sixth minute, whereas the management formulation D12 shows the 99% drug release at 20th minute. Overall, this method is novel and most helpful for formulation into quick dissolving tablets.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords