alexa Human Immunodeficiency Virus and Hepatitis B Virus Dual Infection in Nepal | OMICS International | Abstract
ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
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Research Article

Human Immunodeficiency Virus and Hepatitis B Virus Dual Infection in Nepal

Barnawal SP1*, Niraula SR2, Bista N1, Agrahari AK1, Jha N2 and Pokharel PK2
1B P Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal
2School of Public Health and Community Medicine, BPKIHS, Nepal
Corresponding Author : Satish Prasad Barnawal
B P Koirala Institute of Health Sciences
Dharan, Sunsari, Nepal
Tel: +9779841729232
E-mail: [email protected]
Received March 25, 2014; Accepted May 02, 2014; Published May 10, 2014
Citation: Barnawal SP, Niraula SR, Bista N, Agrahari AK, Jha N, et al. (2014) Human Immunodeficiency Virus and Hepatitis B Virus Dual Infection in Nepal. J Infect Dis Ther 2:142. doi: 10.4172/2332-0877.1000142
 
Copyright: © 2014 Barnawal SP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 
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Abstract

Background: Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HBV) infections are emerging public health problems, particularly in developing counties like Nepal. The study aims at finding prevalence and pattern of CD4 cell count among HBV co-infected HIV positive individuals in Nepal.

Methods: This is a descriptive cross-sectional study carried out in three Volunteer Counseling and Testing (VCT) clinics, one from Dharan and two from Kathmandu Nepal.

Results: 5.75% of HIV infected individuals had HBV dual infection. 33.4% of patients who harbored dual HIV and HBV infection had multiple sex partners. No significant association was observed between HBV co-infection and Injecting Drug Users (IDU). The mean CD4 cell count was found to be significantly more among HBV uninfected cases compared to HBV infected ones at six months’ duration (P=0.006) and one years’ duration (P=0.027) after taking anti-retroviral therapy (ART).

Conclusion: HBV co-infection was more among those having multiple sex partners. ART helped increase CD4 cell count among HBV co-infected and uninfected HIV positive patients, but the results were better among HIV mono-infected individuals.

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