Importance of Drug Safety and Efficacy W.S.R to Strychnos Nux Vomica Detoxification
|Neetu1, Harish Kumar Singhal2*, Sharma KC3 and Chakar pany Sharma4|
|1Lecturer, Department of Ras shastra, Punjab Ayurved College, More zenda Khari, Sri ganganagar, Rajasthan, India|
|2Assistant Professor, Department of Kaumarbhritya, Dr. S.R. Rajasthan Ayurved University, Jodhpur, Rajasthan, India|
|3Reader, P.G Department of Ras shastra, Rishikul Ayurvedic PG College, Haridwar, Uttarakhanda, India|
|4Professor and Head, Department of Dravya Guna, Dr. S.R. Rajasthan Ayurved University, Jodhpur, Rajasthan, India|
|Corresponding Author :||Harish Kumar Singhal
Assistant Professor, Department of Kaumarbhritya
Dr. S.R. Rajasthan Ayurved University
Jodhpur, Rajasthan, India
|Received May 28, 2013; Accepted July 17, 2013; Published July 24, 2013|
|Citation: Neetu, Singhal HK, Sharma KC, Sharma CP (2013) Importance of Drug Safety and Efficacy W.S.R to Strychnos Nux Vomica Detoxification. J Homeop Ayurv Med 2:125. doi: 10.4172/2167-1206.1000125|
|Copyright: © 2013 Neetu, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
The medicine in present era is much advanced and evidence based. Ayurveda offers a unique opportunity to evolve a science of healthy, harmonious and long life. Its holistic approach to health and disease, involving body, mind and spirit, can provide a broader framework to understand research data emerging from reductionist biomedical Sciences. A fresh perspective on the scope of scientific research on the basic concepts of Ayurveda came from a decadal vision document highlighting the importance of Ayurvedic biology. In ancient system of healing all Ayurvedic drug formulation have an inbuilt safety profile but it is necessary to produce the evidence based documents for the safety and efficacy of Ayurvedic drugs. Therapeutic efficacy of any drug or formulation mainly depends on quality control of pharmaceutical processes.
The branch – Rasashastra (Alchemy) is based on the uses of metals and minerals for the therapeutics. It refers various techniques for the purification and detoxification of metallic or mineral ingredients, ie., - Purification, Marana, Amratikaran, Jarana, etc. A great debate is emerging time to time that the Rasa drugs are not safe. They are toxic. The facts speak that the toxicity and adverse effect of Rasa drugs occurs due to avoiding or the negligence of classical references of safety and efficacy, as mentioned in Ayurveda. Modern pharmaceutical science gives stress to the application of SOP (Standard Operating Practice) in the drug manufacturing.
Furthermore, Ayurveda refers “A wise physician may use the poisonous material like nectar but with following the directions, which are time tested and safe.” The ancient sages advocates and emphasize to following the proper classical drug manufacturing methodology, which starts from the authentication to the finished product. It may be given name SOP (Standard Operating Practice). Moreover, the ancestors refers that like the minerals and metals the
medicinal plants which posses the poisonous property should also be detoxified first. Strychnos Nux-vomica contains the poisonous substances which may harm to body. , But, Ayurveda refers its therapeutic uses at various places. For the use of Strychnos Nux-vomica it is clearly mentioned in Ayurveda that this drug should be purified and detoxified first. Present paper is an attempt to explore the Ayurveda principles of Standard Operational Practice wsr to the Strychnos Nux-vomica, supported by the current studies and scientific evidences. The outcome of paper may open the path for the drug standardization, safety, efficacy and quality control.