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Low Starch/Low Dairy Diet Results in Successful Treatment of Obesity and Co-Morbidities Linked to Polycystic Ovary Syndrome (PCOS) | OMICS International | Abstract
ISSN: 2165-7904

Journal of Obesity & Weight Loss Therapy
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Research Article

Low Starch/Low Dairy Diet Results in Successful Treatment of Obesity and Co-Morbidities Linked to Polycystic Ovary Syndrome (PCOS)

Jennifer L. Phy1*, Ali M. Pohlmeier2,3, Jamie A. Cooper2, Phillip Watkins4, Julian Spallholz2, Kitty S. Harris5, Abbey B. Berenson3 and Mallory Boylan2
1Texas Tech University Health Sciences Center, Department of OB-GYN, Center for Fertility & Reproductive Surgery, Lubbock, TX, USA
2Texas Tech University, Department of Nutritional Sciences, Lubbock, TX, USA
3University of Texas Medical Branch, Department of OB-GYN, Center for Interdisciplinary Research in Women’s Health, Galveston, TX, USA
4Texas Tech University Health Sciences Center, Clinical Research Institute, Department of Statistics, Lubbock, TX, USA
5Texas Tech University, Center for the Study of Addiction and Recovery, Lubbock, TX, USA
Corresponding Author : Jennifer L. Phy
DO, FACOG, 3502 9th Street
Suite G-10, Lubbock, TX 79415, USA
Tel: (806)743-4256
Fax: (806)743-4462
E-mail: [email protected]
Received March 18, 2015; Accepted April 25, 2015; Published April 30, 2015
Citation: Phy JL, Pohlmeier AM, Cooper JA, Watkins P, Spallholz J, et al. (2015) Low Starch/Low Dairy Diet Results in Successful Treatment of Obesity and Co-Morbidities Linked to Polycystic Ovary Syndrome (PCOS). J Obes Weight Loss Ther 5:259. doi:10.4172/2165-7904.1000259
Copyright: © 2015 Phy JL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Polycystic Ovary Syndrome (PCOS) affects approximately 15% of reproductive-age women and increases risk of insulin resistance, type 2 diabetes mellitus, cardiovascular disease, cancer and infertility. Hyperinsulinemia is believed to contribute to or worsen all of these conditions, and increases androgens in women with PCOS. Carbohydrates are the main stimulators of insulin release, but research shows that dairy products and starches elicit greater postprandial insulin secretion than non-starchy vegetables and fruits. The purpose of this study was to determine whether an 8-week low-starch/low-dairy diet results in weight loss, increased insulin sensitivity, and reduced testosterone in women with PCOS. Methods: Prospective 8-week dietary intervention using an ad libitum low starch/low dairy diet in 24 overweight and obese women (BMI ≥25 kg/m2 and ≤45 kg/m2) with PCOS. Diagnosis of PCOS was based on the Rotterdam criteria. Weight, BMI, Waist Circumference (WC), Waist-to-Height Ratio (WHtR), fasting and 2-hour glucose and insulin, homeostasis model assessment of Insulin Resistance (HOMA-IR), HbA1c, total and free testosterone, and Ferriman-Gallwey scores were measured before and after the 8-week intervention. Results: There was a reduction in weight (-8.61 ± 2.34 kg, p<0.001), BMI (-3.25 ± 0.88 kg/m2, p<0.001), WC (-8.4 ± 3.1 cm, p<0.001), WHtR (-0.05 ± 0.02 inches, p<0.001), fasting insulin (-17.0 ± 13.6 μg/mL, p<0.001) and 2- hour insulin (-82.8 ± 177.7 μg/mL, p=0.03), and HOMA-IR (-1.9 ± 1.2, p<0.001) after diet intervention. Total testosterone (-10.0 ± 17.0 ng/dL, p=0.008), free testosterone (-1.8 pg/dL, p=0.043) and Ferriman-Gallwey scores (-2.1 ± 2.7 points (p=0.001) were also reduced from pre- to post-intervention. Conclusion: An 8-week low-starch/low-dairy diet resulted in weight loss, improved insulin sensitivity and reduced testosterone in women with PCOS.

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