alexa Malignancies after Chernobyl Accident: What Is True and What Is Untrue | OMICS International| Abstract

Diagnostic Pathology: Open Access

  • Short Communication   
  • Diagn Pathol Open 2016, Vol 1(1): 107
  • DOI: 10.4172/2476-2024.1000107

Malignancies after Chernobyl Accident: What Is True and What Is Untrue

Sergei V. Jargin*
Peoples’ Friendship University of Russia, Moscow, Russia
*Corresponding Author : Sergei V. Jargin, Peoples’ Friendship University of Russia, Clementovski Per 6-82; 115184 Moscow, Russia, Tel: +7(495) 433-73-85, Email: [email protected]

Received Date: Jan 22, 2016 / Accepted Date: Feb 22, 2016 / Published Date: Feb 26, 2016

Abstract

Several publications in the field of pathology, overestimating medical consequences of the Chernobyl nuclear accident, are reviewed here. Among the causes of high registered incidence of pediatric thyroid cancer after the accident was the screening effect with detection of advanced cases. This explains also for the relatively high prevalence of dedifferentiated histological patterns and pronounced invasiveness described as the features of Chernobyl-related thyroid cancer. Mechanisms of false-positive diagnostics of thyroid and urinary bladder lesions are analyzed here. Morphological features of renal cell carcinoma from Chernobyl and adjacent areas are discussed in relation to the averagely late detection of malignancies. In conclusion, results of some molecular-genetic and other studies based on Chernobyl material should be re-evaluated, considering that many tumors detected during the first decade after the accident by the screening or brought from non-contaminated areas were advanced tumors, some of them misinterpreted as aggressive radiogenic cancers developing after a short latency.

Keywords: Chernobyl; Ionizing radiation; Thyroid cancer; Renal cell carcinoma; Urothelial malignancy

Citation: Jargin SV (2016) Malignancies after Chernobyl Accident: What Is True and What Is Untrue. Diagn Pathol Open 1: 107. Doi: 10.4172/2476-2024.1000107

Copyright: ©2016 Jargin SV. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Review summary

  1. Paula Unger
    Posted on Aug 24 2016 at 2:01 pm
    The article discusses the impact of Chernobyl accident on the incidence of paediatric thyroid cancer. The rates of occurrence of thyroid cancer in infants are used as the screening factor to access the harmful and long lasting impact of the accident. The article is highly significant and will help in the development of combat mechanisms for dealing with the occurrence of such diseases.
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