Microvascular Perfusion Changes in the Contralateral Gastrocnemius Following Unilateral Eccentric Exercise
|Noelle M Selkow1, Daniel C Herman2, Zhenqi Liu3, Jay Hertel3, Joseph M Hart3 and Susan A Saliba3|
|1School of Kinesiology and Recreation, Illinois State University, USA|
|2Primary Care Sports Medicine Fellow, University of Florida, USA|
|3University of Virginia, USA|
|Corresponding Author :||Noelle M Selkow
School of Kinesiology and Recreation
Illinois State University, Campus Box 5120
Normal, Il 61761, USA
E-mail: [email protected]
|Received May 16, 2013; Accepted June 26, 2013; Published June 28, 2013|
|Citation: Selkow NM, Herman DC, Liu Z, Hertel J, Hart JM, et al. (2013) Microvascular Perfusion Changes in the Contralateral Gastrocnemius Following Unilateral Eccentric Exercise. J Nov Physiother 3:163. doi: 10.4172/2165-7025.1000163|
|Copyright: © 2013 Selkow NM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Context: Eccentric exercise increases local blood flow and volume as a result of increased metabolic demand. It is not known how eccentric exercise affects microvascular perfusion in the musculature of the opposite limb over this 48 hour period.
Objective: To quantify microvascular perfusion immediately after eccentric exercise to the gastrocnemius in the opposite limb and over 48 hours following the exercise.
Design: Descriptive laboratory study. Setting: Laboratory.
Patients or Other Participants: Six healthy participants volunteered (1M, 5F; Age: 22.4 ± 2.1 years; Height: 165.2 ± 16.6 cm; Weight: 64.5 ± 25.1 Kg).
Intervention(s): A unilateral, eccentric exercise was performed to a randomized leg. Each subject performed 100 calf-lowering repetitions in the sequence of 50 repetitions, 5 min rest and 50 repetitions.
Main outcome measure: Micro vascular perfusion measurements (blood volume (dB), blood flow (dB/sec), and blood flow velocity (1/sec)) of the contralateral gastrocnemius were taken using contrast-enhanced ultrasound (CEU) at baseline, immediately after exercise, and 48 hours after exercise. Pain using a visual analog scale was also recorded baseline, 24, and 48 hours after exercise to determine the onset of delayed onset muscle soreness (DOMS).
Results: There was a significant increase in blood volume immediately after exercise (9.77 ± 3.19 dB) from baseline (6.18 ± 2.05 dB) (p=.023). There was a significant increase in blood flow immediately after exercise (3.53 ± 0.86 dB/sec) from baseline (2.40 ± 0.69 dB/sec) (p=.010). There was no change in blood flow velocity (p=0.487). Blood flow (p=0.003) and volume (p=0.002) remained significantly higher at 48 hours from baseline, with no change in blood flow velocity (p=0.316). Pain significantly increased.
Conclusion: Micro vascular perfusion increased immediately after exercise in the contralateral gastrocnemius. This increase was maintained following a single bout of eccentric exercise over a 48 hour period in the presence of DOMS.