Study of the Effect of Magnetic Microspheres on Some Biophysical Parameters of Human Blood (<em>In vitro</em> Study) | OMICS International | Abstract
ISSN: 2155-952X

Journal of Biotechnology & Biomaterials
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Study of the Effect of Magnetic Microspheres on Some Biophysical Parameters of Human Blood (In vitro Study)

Abdelrahman T Hereba, Mohamed A Elblbesy* and Mamdouh M Shawki

Bio-Medical Physics Department, Medical Research institute, Alexandria University, Egypt

Corresponding Author:
Mohamed A. Elblbesy
Bio-Medical Physics Department, Medical Research Institute
Alexandria University, Egypt
Tel: +2-0124380086
Fax: +2-03-4283719
E-mail: [email protected]

Received date: December 14, 2011; Accepted date: April 12, 2012; Published date: April 14, 2012

Citation: Hereba AT, Elblbesy MA, Shawki MM (2012) Study of the Effect of Magnetic Microspheres on Some Biophysical Parameters of Human Blood (In vitro Study). J Biotechnol Biomater 2:135. doi:10.4172/2155-952X.1000135

Copyright: © 2012 Hereba AT, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Magnetic microspheres have many bio-medical applications, but they have contact with the blood before reaching to their target place in many cases, so the study of the effect of these microspheres on the blood can lead to optimization of the use of these microspheres. Five groups of normal blood samples were incubated with 10 mg magnetic chitosan microspheres for 1, 3, 6, 12, and 24 hours (h) respectively, then each group was compared to control group samples. The results showed that increase in hemoglobin conductivity with the time of incubation, no change in red blood cells osmotic fragility, no change in hemoglobin absorbance spectrum. Decrease in blood pH at 24 h, no change in neither hemoglobin electrophoretic patterns or in the blood components ultra structures. These results indicated no obvious toxicity of the magnetic microspheres on blood for incubation time up to 24 h, but on the other hand there are some changes especially at 24 h of incubation, so it is safer to avoid the remaining of the microspheres inside the body for more than 24 h.

Recommended Conferences

2nd International Conference on Biotechnology and Healthcare

Auckland, New Zealand
Indexed In
  • Index Copernicus
  • Google Scholar
  • Sherpa Romeo
  • Open J Gate
  • Genamics JournalSeek
  • Academic Keys
  • ResearchBible
  • China National Knowledge Infrastructure (CNKI)
  • Access to Global Online Research in Agriculture (AGORA)
  • Electronic Journals Library
  • RefSeek
  • Hamdard University
  • OCLC- WorldCat
  • SWB online catalog
  • Virtual Library of Biology (vifabio)
  • Publons
  • Geneva Foundation for Medical Education and Research
  • Euro Pub
Share This Page