Effect Of Non-pharmacological Interventions On Functional Performance In Mild Cognitive Impairment (MCI): A Scoping Review | 57466
Journal of Alzheimers Disease & Parkinsonism
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Mild Cognitive Impairment (MCI) is one of the most recognized risk factors for dementia. It affects approximately 19%
of the individuals over 65 years of age (Lopez et al., 2003) It is now recognized that these individuals are independent in
performing everyday activities, but “take more time, are less efficient and make more errors”(Albert et at., 2011). Few studies
have investigated the effects of non-pharmacological interventions in improving functional performance in this population.
Thus, the aims of this study were to identify the non-pharmacological interventions which have been targeted at improving
functional performance in individuals with MCI. To conduct a scoping review, a systematic electronic search was executed in
following bibliographic databases: Ovid Medline (1999-2014), CINAHL (1999-2014), PsychINFO (1987-2014). Publications
which estimated the effect of any non-pharmacological approaches in MCI and had instrumental activities of daily living
(IADLs) as one of their outcomes of interest, were deemed eligible. Data were extracted on the author, publication year, target
population, study design, MCI diagnostic criteria, nature of the intervention, functional outcome measure and the outcome. Ten
studies fulfilled the eligibility criteria. Four studies focussed on exercise training, five evaluated behavioural interventions and
one combined both exercise and cognitive stimulation. Overall, exercise interventions reported improvements in functional
abilities. The effect of behavioural interventions varied across studies. Combined aerobic training and cognitive stimulation did
not yield any benefits in improving IADLs. Exercise studies seem promising, whereas the behavioural interventions illustrated
mixed results. The findings of the review highlight more rigorous research is required in this area with specific considerations
to methodology, follow-up duration, MCI criteria and IADL measures.
Navaldeep is a doctoral student in Rehabilitation Science at the McGill University, Canada. She completed her MSc in Exercise Science from the University of East London in the year 2010. Her research interests are focussed on individuals with Alzheimer’s disease (AD) and mild cognitive impairment (MCI).