Journal of Gastrointestinal & Digestive System
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Non-cirrhotic portal hypertension (NCPH) represents a distinct group of conditions that cause portal hypertension
in absence of cirrhosis. The causes of NCPH are different in adult and pediatric populations. An imaging review of conditions
causing NCPH in adults is presented.
Introduction to NCPH
Classification of NCPH: intrahepatic presinusoidal, extrahepatic presinusoidal, sinusoidal, intrahepatic post-sinusoidal and
extrahepatic post-sinusoidal NCPH
Clinical presentation and pathophysiology of NCPH
Cross-sectional and MDCT imaging spectrum of NCPH with histo-pathological correlation
NCPH is commonly caused by elevated portal venous outflow resistance, although rarely hyperkinetic portal
circulation may be responsible. Pathophysiologically the causes can be categorized into three groups based on whether the
abnormality is at portal venous level, in sinusoidal bed or at hepatic veins. Clinical presentation of these groups can be varied and
imaging plays an important role. Background knowledge of pathophysiology and symptomatology helps in accurate diagnosis
and optimal care.
Abhijit Sunnapwar is dual board certified radiologist (in India and USA). He is working as Assistant Professor of Radiology at the University of Texas
Health Science Center at San Antonio for last four years. He has nine publications in Pubmed indexed journals. He is also a reviewer of three
radiology journals. His expertise includes imaging of GI and GU and image guided interventions with special interest in MRI. He is Chief of body
MRI at University hospital, San Antonio. He has presented in National and International medical conferences with over 40 educational exhibits and
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