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Pivotal Role Of Tailored Lifestyle Modification In The Management Of Pcos | 110328
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Statement of the problem:- PCOS is a complex disorder with reproductive, and metabolic manifestations.
Global incidence is 1 in every 5 women. The purpose of this study is to assess how the extra vigilant and
sensitized approach including lifestyle modification and nonhormonal medical management produces
comparable results to LOD and reverses the symptoms of PCOS.
Methodology:- We studied 274 patients in the 17- 45 year age group, between January 2017 to February
2023. The diagnosis was made on basis of the Rotterdam Criteria. Hormonal evaluation, HOMA-IR, and
QUICKI were done. Each patient is given a questionnaire about her lifestyle including her sleep, wakeup
time, diet, utensils, cooking oil, etc. A tailored lifestyle modifying three pillars of nutrition, exercise, and
behavior was introduced to each patient. Nutraceuticals were introduced as insulin sensitizers, Myo and
D-chiro inositol combination, antioxidants; zinc, chromium, selenium, and lactoferrin to 134 patients. 140
patients with severe hormone derangement were treated with the above treatment for 9-12 months plus
OCPs for 3 months.
Results:- Among 134 patients, after 6-9 months of treatment 130 patients restore spontaneous cycles, able
to conceive spontaneously, lose weight, decreased mood swings, and improved HOMA-IR and QUICKI.
68 infertile out of 140 severe PCOS patients were able to conceive in 2-3 cycles of ovulation induction,
and 34 lost significant fat, 20 restored cycles. Only 3 patients who failed to respond to 9-12 months of the
above treatment were offered LOD and were able to conceive, then. 19 patients were lost to follow-up.
Conclusion:- Vigorous, personalized lifestyle modification teaches every patient about pathogenesis and
how can she correct the root cause so as to beat PCOS for a lifetime. Active participation of the patient
in designing her diet, exercise, and positive mindset manual brings optimistic results and nonhormonal
treatment motivates patients to be compliant with the treatment.
keywords- LOD-Laparoscopic Ovarian Drilling, HOMA-IR- Homeostatic Model Assessment Insulin
Resistance Index; QUICKI-Quantitative Insulin sensitivity Check Index; OCP- Oral Contraceptive pills
References:-
1. Siew S Lim, corresponding author Samantha K Hutchison, Emer Van Ryswyk, Robert J Norman,
Helena J Teede, Lisa J Moran, and Cochrane Gynaecology and Fertility Group. Lifestyle changes in
women with polycystic ovary syndrome.Cochrane Database Syst Rev. 2019; 2019(3): CD007506.
2. ALY, JASMINE M. MD; DECHERNEY, ALAN H. MD. Lifestyle Modifications in PCOS.Clinical
Obstetrics and Gynecology 64(1):p 83-89, March 2021.
3. Bharti Kalra, Sanjay Kalra,1 and J. B. Sharma2.The inositols and polycystic ovary syndrome. Indian J
Endocrinol Metab. 2016 Sep-Oct; 20(5): 720–724.
4. Philippe Merviel, Pandora James, Sarah Bouée, Mathilde Le Guillou, Camille Rince, Charlotte
Nachtergaele & Véronique Kerlan. Impact of Myo-inositol treatment in women with polycystic ovary
syndrome in assisted reproductive technologies.Reproductive Health volume 18, Article number: 13
(2021)
5. Leila Amini, Ph.D. candidate,1 Najmeh Tehranian, Ph.D.,1 Mansoureh Movahedin, Ph.D.,2 Fahimeh
Ramezani Tehrani, M.D.,3 and Saeedeh Ziaee, M.D.1 Antioxidants and management of polycystic ovary
syndrome in Iran: A systematic review of clinical trials. Iran J Reprod Med. 2015 Jan; 13(1): 1–8.
Biography
Dr.Shradha Goel is the Director and founder of PCOSmetic Gyne Clinic, Jaipur, India which is a unique center of its type in the region. She has a passion to provide sophisticated and novel solutions for entire phenotypes of PCOS under one roof. She has done detailed research for years to study lifestyle modification in PCOS patients and came up with an integrated & scientific model to open new pathways for the best treatment. She follows a personalized approach where patients of PCOS are taught the pathogenesis of the disorder so as to learn how to increase insulin sensitivity. Combining cosmetology and functional gynecology for the treatment of cosmetic phenotypes of PCOS helped her patients to enhance their self-confidence. She believes in the multidisciplinary approach to treating PCOS. She has completed her medical school with MBBS and Master in Obstetrics and Gynecology from the esteemed Institute of Medical Sciences, Banaras Hindu University Varanasi.
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