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Prevalence And Implications Of Coeliac Disease In Undetected Adults Compared To Those Diagnosed With Irritable Bowel Syndrome (IBS) In Riyadh, Saudi Arabia | 25238
ISSN: 2161-069X
Journal of Gastrointestinal & Digestive System
Open Access
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Prevalence and implications of coeliac disease in undetected adults compared to those diagnosed with irritable bowel syndrome (IBS) in Riyadh, Saudi Arabia
3rd International Conference on Gastroenterology & Urology
A study of 720 adults, half of them randomly selected as a control, for undetected coeliac disease of males and females,
aged between 20 and 60 from students and employees in two Riyadh Colleges of Health Sciences were conducted.
It was also compared the same number of 360 cases with a randomly selected group diagnosed with irritable bowel syndrome
from Al-Iman Hospital at Riyadh, Saudi Arabia, within the same age range and similar mixed gender distribution. The control
consisting of undetected coeliac disease and the cases with Irritable Bowel Syndrome (IBS), both randomly selected, were
tested for autoimmune antibodies to tissues transglutaminase (tTGAs) and endomysial autoantibody (EMAs) as serological
predictors of coeliac disease and positive patients of coeliac disease were confirmed by histopathology test. The confirmed cases
of coeliac disease were tested for iron deficiency anaemia, Vitamin D deficiency, osteoporosis and weight assessment. In the
undetected control, the percentage of coeliac disease was found to be 1.9%, slightly higher than the percentage world wide range
in adults with undetected coeliac disease. However, in patients diagnosed as irritable bowel syndrome (IBS) the percentage was
found to be almost five times to that of the control at 9.5%. These findings might explain that given a considerable similarity of
symptoms of coeliac disease and irritable bowel syndrome, can lead to the over-diagnosis of irritable bowel syndrome, or on
the other hand misdiagnosis of coeliac disease.
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