Therapeutic Potential Of Bacillus Probiotics For Enteric Disease | 3504
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Therapeutic potential of Bacillus probiotics for enteric disease

2nd International Conference on Gastroenterology & Urology

Iryna Sorokulova

AcceptedAbstracts: J Gastrointest Dig Syst

DOI: 10.4172/2161-069X.S1.019

Bacillus bacteria are gaining wider attention as more scientific data confirm beneficial effects of these microorganisms on the host. Bacillus bacteria were shown to produce digestive and lytic enzymes, essential amino acids and vitamins, antibiotics with unique spectrum of activity, and other biologically active substances. Bacilli are traditionally used in some countries as starter cultures for food preparation. We isolated and thoroughly examined a new B. subtilis strain with broad spectrum of antagonistic activity against pathogens. High activity of this strain against pathogenic microorganisms, determined in vitro, was confirmed in animal studies. Oral treatment of mice with probiotic culture was effective in protecting of animals against experimental Campylobacter infection. High efficiency of B. subtilis strain in treatment of acute diarrhea was demonstrated in randomized double-blind controlled clinical trials, conducted according to the approved protocol. Treatment of patients with salmonellosis and shigellosis resulted in complete elimination of pathogens from intestine in 3 ? 4 days without antibiotic therapy. No side effects or treatment-related complications were found during clinical trials. Bacillus bacteria have a great potential as probiotics and therapeutics.
Iryna Sorokulova is a Professor of Microbiology, Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, USA. She received her M.S. degree in Microbiology from Taras Shevchenko Kiev State University (Ukraine) and Ph.D. and D.Sc. degrees in Microbiology from Institute of Microbiology and Virology, National Academy of Sciences of Ukraine. She has received a solid background in formulation and regulation of biological products during the training courses in Bureau of Biologics (Ottawa, Canada) and Massachusetts Biologic Laboratories (Boston, USA). Dr. Sorokulova is the author of 73 refereed scientific publications, 4 books, and 23 patents.