Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar
GET THE APP
Utilization Of LC For The Physicochemical And Thermodynamic Characterization Of Forming Cilostazol Inclusion Complexes With β-CD And DM-β-CD | 18735
ISSN: 2155-9872
Journal of Analytical & Bioanalytical Techniques
Open Access
Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
In this presentation, the interaction between cilostazol and two different cyclodextrins (β-CD and DM-β-CD) is studied
by using LC. The capacity factors (k) of cilostazol were monitored in the presence of increasing concentrations of β-CD
or DM-β-CD from the reduction of the retention time (tR). It was observed that cilostazol forms a 1:1 inclusion complex
with β-cyclodextrin (β-CD) and dimethyl-β-cyclodextrin (DM-β-CD) at 25
0
C, 37
0
C and 45
0
C. The interaction of cilostazol
with DM-β-CD was more efficient and the highest the formation constant (K) was found for DM-β-CD (23.82M-1) at 25
0
C.
Moreover, the values of K decreased as the system temperature increased. To obtain the information on the mechanism of
cilostazol affinity for β-CD and DM-β-CD, the thermodynamic parameters of the complexation (ΔG, ΔH, and ΔS) were
studied. Finally, a comparison of the K values obtained for the two different cyclodextrins revealed that the K values of the
complexation are dependent upon the structure of the host molecule. The change in the thermodynamic parameters suggested
that the complexation could proceed spontaneously (ΔG<0) along with the releasing of heat (ΔH<0) and the decrease of
entropy (ΔS<0).
Biography
Relevant Topics
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals