alexa Abstract | Neurovascular complication of Hematologic Disorders: Case of Deficits in S and C Proteins about an Observation in Abidjan Ivory Coast
ISSN: 2572-5645

Advances in Molecular Diagnostics
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Case Report Open Access

Abstract

The frequency of cerebral infarcts associated to a hematologic infection remains difficult to be known and imprecise. The deficit of S and C protein is rarely responsible for cerebral infarcts. We thus bring a young Ivorian patient hospitalized in our neurologic service. She consulted for a left hemi corporal motor deficit of a brutal installation without a particular context. The clinical examinations found a left proportional hemiparesis at 2/5 in superior and inferior members according to the Medical Research Council scale (MRC) and a left painful hemi hypoesthesia. The rest of the examination was without particular. The Neurovascular imagery has objective various cerebral infarcts. Cardiovascular etiologies and hematologic checkups were strictly normal apart from the reduction of the prothrombin percentage (TP=32%). The C protein had reduced (C protein=47% NV>70) and the S protein had equally reduced (S protein=27% NV˃60). Other factors of dependent Vitamin K coagulation, (factors II VII IX and X) was also reduce. In front of these results and the absence of other causes which can explain its pathology, the diagnoses of multiple cerebral infarcts due to a deficit in S and C protein had be retained. The patient benefitted a treatment of acetylsalicylic acid 100 mg/day and of vitamin K oral route; a symptomatic treatment and a physical reeducation. The evolution was marked six weeks after by a takeover of walk. A motor recuperation at the level of the left side of the body from 2/5-4/5 and a disappearance of a sensitive disorder of the same side. The rarity of deficits in S and C proteins is difficult to put in evidence their implication in the up come of a cerebral infarcts which can cause or lead to an interest to think in front of all vascular event of a young subject

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Author(s): Zakaria Mamadou, Soumaila Boubacar, Constance Yapo Ehounoud, Eric Bila and Aka Anghui Diarra Evelyne

Keywords

Cerebral infarcts, C and S proteins, Hematologic disorders, Abidjan, Cardiovascular Diagnosis,Clinical Diagnosis

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