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My research focuses on understanding how molds and other fungi cause human disease. Recently, our laboratory discovered that fungi secrete sugars that can act as a glue in order to help fungi attach to human lung cells and hide from the immune system during lung infections. My research focuses on fungi that infect humans. In particular, we focus on the common mold Aspergillus fumigatus, which causes pneumonia in patients who have received chemotherapy, organ transplantation, bone marrow transplantation or high dose cortisone therapy. Despite the use of current antifungal drugs, this pneumonia is fatal for more than half the affected patients. Our group is working to identify how this fungus invades human tissues in order to develop new, more effective antifungal therapies to prevent and cure this aggressive and common condition.
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