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Halmuthur.M.Sampath Kumar, obtained his MSc degree (Organic Chemistry) from Gulbarga University, India and PhD from CSIR- Indian Institute of Chemical Technology, Hyderabad(1995) in the area of Biomimetic Chemistry. He later moved to Max Planck Institute, Dortmund in the year 2000 to work as Humboldt Fellow with Prof. Herbert Waldmann in the area of gene therapy. After returning to India, he continued his research at CSIR-IICT in the area of agrochemical and pharmaceutical technology development. Subsequently, he relocated to Regional Research Laboratory(2004)-Jammu and initiated major projects on vaccine adjuvants and cosmeceuticals research. His team developed novel plant based semisynthetic immune adjuvants and skin care hybrid molecules as major collaboarative projects with P&G and Colgate Plamolive on oral and skin care product development. He served as the Chairman of the Synthetic and Biological Chemistry Department of CSIR-IIIM, Jammu till 2009. He is the nodal scientist for the vaccine immunology programme at CSIR-IICT, Hyderabad. Focus of his current research is on the development of novel small molecule immunomodulators, and vaccine(Th1) adjuvants. and peptide based synthetic vaccines for cancer and other diseases involving intracellular pathogenesis.
• Discovery of novel Immunomodulators, Development of Novel Th1/Th2 adjuvants for subunit vaccines. peptide epitope based wholly synthetic vaccines • Cosmeceuticals: Perfumery Hybrid s, herbal cosmeceuticals, multiple action skin care products • Natural product scaffold modification for new lead discovery. • Target based drug design. Structural modifications of natural products as a means of new lead discovery and synthesis of focused libraries of target interactive ligands based on natural products • Bio-conjugate chemistry/medicinal chemistry. • Solid phase synthesis of carrier peptide-conjugates and their application in plant secondary metabolic engineering and gene therapy. • Anticancer, anti-infective hybrid molecules. • Development of cancer vaccines based on tumor associated glycopeptide antigens. • Total synthesis of complex carbogenic molecules and development of new synthetic methods. Novel combinatorial methodologies.
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