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Assessment of Drug Related Problems Among Hypertensive Patients on Follow up in Adama Hospital Medical College, East Ethiopia | OMICS International | Abstract
ISSN: 2167-065X

Clinical Pharmacology & Biopharmaceutics
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Review Article

Assessment of Drug Related Problems Among Hypertensive Patients on Follow up in Adama Hospital Medical College, East Ethiopia

Mohammednur Hussein, Jimma Likisa Lenjisa*, Minyahil Alebachew Woldu, Gobeze Temesgen Tegegne, Gurmu Tesfaye Umeta, Hunduma Dins and Belayneh Kefale Gelaw
Department of Pharmacy, College of Medicine and Health Science, Ambo University, Ambo, Ethiopia
Corresponding Author : Jimma Likisa Lenjisa
Department of Pharmacy
college of medicine and health science
Ambo university, Ambo, Ethiopia
Tel: +251913805290
E-mail: [email protected]
Received August 22, 2014; Accepted September 19, 2014; Published September 23, 2014
Citation: Hussein M, Lenjisa JL, Woldu MA, Tegegne GT, Umeta GT, et al. (2014) Assessment of Drug Related Problems Among Hypertensive Patients on Follow up in Adama Hospital Medical College, East Ethiopia. Clin Pharmacol Biopharm 3:122. doi:10.4172/2167-065X.1000122
Copyright: Hussein M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Hypertension is an important worldwide public-health challenge because of its high frequency and risk factor for cerebrovascular, cardiovascular and kidney disease. Drug therapy problems are a significant challenge to health care providers. It severely compromises the effectiveness of treatment making this a critical issue in population health both from the perspective of quality of life and of health economics. Therefore, the objective of this study is to determine the pattern and magnitude of drug therapy problems in the study hospital and to find out risk factors for these problems. The study was questionnaire-based Cross sectional design which was conducted from April to May 2014 at Adama Hospital Medical College. A convenient sampling method was used and a total of 192 hypertensive patients were included in the study. Data were analyzed using SPSS software program. In this study 155 (80.7%) patients have at least one drug therapy problem and a total of 452 drug therapy problems were identified in them. The most common drug therapy problem identified in this study was drug interaction (n=259, 58.7%), followed by non-adherence and adverse drug interaction constituting 19.5% and 18.6% respectively. Under dose accounts only 0.9% of all drug therapy identified. Marital status, number of drugs and number of co morbidities significantly affect drug therapy problems. The study showed that 80.7% of the patients in the study have drug therapy problems. Number of complications and number of drugs significantly affect drug therapy problems. Therefore, patients with multiple diagnosis and patients using multiple drugs should be closely monitored for drug therapy problem, to avoid clinically significant harmful consequences.

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