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Scedosporium Prolificans Sclerokeratitis Following Pterygium Excision with Mitomycin C: A Case Requiring Enucleation | OMICS International | Abstract

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Case Report

Scedosporium Prolificans Sclerokeratitis Following Pterygium Excision with Mitomycin C: A Case Requiring Enucleation

Nickisa M Hodgson1, Helen King2, Bradford W Lee1, Deirdre Amaro3, Don O Kikkawa1, Jonathan H Lin3, Bobby S Korn1 and Randy A Taplitz2*

1Division of Ophthalmic Plastic and Reconstructive Surgery, Shiley Eye Institute, University of California, San Diego, California

2Division of Infectious Diseases, Department of Medicine, University of California, San Diego, California

3Department of Pathology, University of California, San Diego, California

*Corresponding Author:
Randy A Taplitz
Division of Infectious Diseases, Department of Medicine
University of California, San Diego, California
Tel: (858) 822-0711
Fax: (858) 822-5322
E-mail: rtaplitz@ucsd.edu

Received date: March 07, 2017; Accepted date: March 27, 2017; Published date: April 05, 2017

Citation: Hodgson NM, King H, Lee BW, Amaro D, Kikkawa DO, et al. (2017) Scedosporium prolificans Sclerokeratitis Following Pterygium Excision with Mitomycin C: A Case Requiring Enucleation. J Emerg Infect Dis 2:125. doi: 10.4172/2472-4998.1000125

Copyright: © 2017 Hodgson NM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Scedosporium prolificans is a rare cause of fungal sclerokeratitis following pterygium excision with beta-irradiation or Mitomycin C (MMC). We present a case of a male horticulturist with history of bilateral pterygium excision with MMC who presented for evaluation of refractory sclerokeratitis and was found to have S. prolificans sclerokeratitis. Despite aggressive topical and combination intravenous antifungal therapy, enucleation of the affected eye was required due to evidence of posterior scleral extension on imaging. S. prolificans should be considered in cases of refractory sclerokeratitis. Infections due to S. prolificans often do not respond to antifungal therapies alone and often require swift surgical management.

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