Seroprevalence of Influenza A (H1N1) pdm09 Infection and Risk Factors Associated in Pikine, Dakar Region, SenegalSylvain Paquet1, Anta Tal-Dia2, Mbayame Ndiaye Niang3, Some Aymar Narodar1, Ndongo Dia3, Debora Goudiaby3, Mayassine Diongue2 and Jean-Yves Le Hesran1*
- *Corresponding Author:
- Jean-Yves les Hesran
UMR 216, Faculty of Pharmacy, 4 avenue de l’Observatoire
75270 Paris cedex – 6, France
Tel: (33) 1 53 73 15 07
Fax: (33) 1 53 73 96 17
E-mail: [email protected]
Received date: November 02, 2016; Accepted date: December 16, 2016; Published date: December 27, 2016
Citation: Paquet S, Tal-Dia A, Niang MN, Narodar SA, Dia N, et al. (2016) Seroprevalence of Influenza A (H1N1) pdm09 Infection and Risk Factors Associated in Pikine, Dakar Region, Senegal. J Emerg Infect Dis 1:119. doi: 10.4172/2472-4998.1000119
Copyright: © 2016 Paquet S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
There is lack of data describing the A (H1N1) pdm09 virus pandemic in Africa. In 2011, we carried out a crosssectional study that aimed to estimate the prevalence of A (H1N1) pdm09 serology in the general population of Pikine, in the region of Dakar, Senegal. 2669 persons from 347 households were tested for A (H1N1) pdm09 using a hemagglutination inhibition test (threshold of 1/80). The general seroprevalence was of 49,0%. Our result showed a pronounced heterogeneity according to neighborhood (16,7%-71%). Multilevel analysis showed that “covering one’s mouth while coughing” was the only variable related to a reduction of A (H1N1) pdm09 infection (OR=0.50 (0.25- 0.98)). Additionally, variance analysis showed significant effects of neighborhood and household. In conclusion, this study showed intense circulation of the A (H1N1) pdm09 virus among the general population in Pikine. The «Neighborhood» and «household» effects identified require elucidation in order to understand the epidemiology of this epidemic.