alexa Using Functional Magnetic Resonance Imaging to Describe
ISSN: 2167-0846

Journal of Pain & Relief
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Research Article

Using Functional Magnetic Resonance Imaging to Describe Pain Pathways in the Oldest Old: A Case Study of a Healthy 97-year-old Female

Todd Monroe1*, Andrew Dornan2, Michael A. Carter3 and Ronald L. Cowan4
1Vanderbilt University School of Nursing, Vanderbilt University Institute of Imaging Science, Nashville, Tennessee, USA
2Vanderbilt Psychiatric Neuroimaging Program, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
3The University of Tennessee Health Science Center College of Nursing, Memphis Tennessee USA
4Vanderbilt Addiction Center, Vanderbilt Psychiatric Neuroimaging Program, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Corresponding Author : Todd Monroe
Vanderbilt University School of Nursing
Vanderbilt University Institute of Imaging Science
461 21st Avenue South, Nashville
Tennessee, USA
E-mail: [email protected]
Received June 20, 2012; Accepted August 21, 2012; Published August 27, 2012
Citation: Monroe T, Dornan A, Carter MA, Cowan RL (2012) Using Functional Magnetic Resonance Imaging to Describe Pain Pathways in the ‘Oldest Old’: A Case Study of a Healthy 97-year-old Female. J Pain Relief 1:111. doi: 10.4172/2167-0846.1000111
Copyright: © 2012 Monroe T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

The prevalence of painful medical conditions increases with age. Pain differences in older adulthood are of special concern because we do not know how brain changes in healthy aging may alter the sensory and affective response to pain. Over the last two decades, neuroimaging studies have described interconnected brain regions that mediate pain processing. In particular, imaging techniques have been used to describe brain activation in networks of structures comprising the lateral and medial pain systems. The lateral and medial pain networks are generally associated with the sensory-discriminative and affective-motivational dimensions of pain respectively. Key structures that are associated with the lateral pain network include specific nuclei in the thalamus and primary (S1) and secondary somatosensory (S2) cortex while different but specific nuclei in the thalamus, as well as regions in the insular and cingulate cortices are associated with the medial pain network

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