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James P Bennett | OMICS International
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
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James P Bennett

USA
Publications

Effect of Lewy Bodies on Mitochondrial DNA Copy Numbers and Deletion Burden in Parkinson's Disease Substantia nigra Neurons

Objective: Our objective was to evaluate mitochondrial DNA (mtDNA) gene copy numbers in substantia nigra neurons from post-mortem Parkinson’s Disease cases and determine if the presence of Lewy bodies (LBs) altered mtDNA copy numbers or changed apparent deletion of mtDNAs. Methods: We used laser capture micro dissection to isolate neuromelani... Read More»

Knarik Arkun, Ann C Rice and James P Bennett

Research Article: J Alzheimers Dis Parkinsonism 2015, 4:175

DOI: 10.4172/2161-0460.1000175

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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