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Lori Daiello | OMICS International
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
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Lori Daiello


Disrupted Blood-CSF Barrier to Urea and Creatinine in Mild Cognitive Impairment and Alzheimer's Disease

Objective: In this pilot study hypothesizing that blood-CSF barrier (BCSFB) function is altered in mild cognitive impairment (MCI), we evaluated small-sized biomarker distribution between serum (SER) and cerebrospinal fluid (CSF). For both MCI and Alzheimer (AD) patients we quantified CSF neurochemistry; and compared CSF/SER ratios for urea and cre... Read More»

Conrad E Johanson, Edward G Stopa, Lori Daiello, Suzanne de la Monte, Matthew Keane and Brian R Ott

Research Article: J Alzheimers Dis Parkinsonism 2018, 8:435

DOI: 10.4172/2161-0460.1000435

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article