Shu-Yuan Cheng | OMICS International

Journal of Cell Science and Apoptosis
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Shu-Yuan Cheng

John Jay College of Criminal Justice, New York 10019

Maneb and Mancozeb Increase Amyloid β Precursor Protein Expression and Activate PKR

Background: Oligomers of amyloid β (Aβ) in the brain correlate with synapse loss and dementia. The fungicide maneb (MB) and mancozeb (MZ) have been shown to activate the transcription factor NF-κB. Activation of NF-κB signaling pathway could initiate the transcription of β-amyloid precursor protein (AβPP) leading to ... Read More»

Shu-Yuan Cheng, Yessenia Lopez and Jazlene Montes

Research Article: J Cell Sci Apo 1: 110

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