Exploring the Role of Perceived Stress in a Patient's Experience of Fibromyalgia | OMICS International | Abstract
ISSN: 2167-0846

Journal of Pain & Relief
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Research Article

Exploring the Role of Perceived Stress in a Patient's Experience of Fibromyalgia

Toussaint LT1, McAllister JS2, Whipple OM2, Aleman K2, Hassett LA4, Oh HT3 and Vincent A2*
1Department of Psychology, Luther College, 700 College Drive, Decorah, Iowa, USA
2Department of Medicine Mayo Clinic, Rochester, Minnesota, USA
3Department of Physical Medicine and Rehabilitation, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, USA
4Department of Anesthesiology , University of Michigan, 1500 E Medical Center Drive, Ann Arbor, Michigan, USA
Corresponding Author : Ann Vincent
Department of Medicine, Mayo Clinic, 200 First Street SW
Rochester, MN 55905, USA
Tel: 507-284-8913
E-mail: ann.vincent[email protected]
Received May 13, 2014; Accepted September 08, 2014; Published September 10, 2014
Citation: Toussaint LT, McAllister JS, Whipple OM, Aleman K, Hassett LA, et al. (2014) Exploring the Role of Perceived Stress in a Patient’s Experience of Fibromyalgia. J Pain Relief 3: 155. doi: 10.4172/2167-0846.1000155
Copyright: © 2014 Toussaint TL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.


The purpose of this exploratory study was to examine cross-sectional relationships between perceived stress and fibromyalgia impact. Also, we sought to examine the mediating effects of key fibromyalgia symptoms including pain, fatigue, unrefreshing sleep, dyscognition, depressed mood and autonomic symptoms on this relationship. Data from 705 patients meeting Fibromyalgia Research Survey Criteria who completed a battery of self-report measures was used. Bivariate correlations revealed that stress was associated with fibromyalgia impact (r=0.49). Stress was also associated with all symptoms assessed (rs=0.29-0.77) and fibromyalgia impact was also associated with these symptoms (rs=0.33-0.59). Mediation modeling revealed that the total effect of stress on fibromyalgia impact was statistically significant (B=0.35,p<0.001), however, the direct effect was not significant when controlling for all mediators (B=0.03,p<0.05) and the total indirect effect of all mediators (B=0.32,p<0.05) was statistically significant and fully explained the association between stress and fibromyalgia impact. Specifically, pain, fatigue, negative mood, and autonomic dysregulation had significant indirect effects on this relationship. Our results demonstrate that perceived stress is associated with the patient’s experience of exacerbated individual fibromyalgia symptoms. Also, the patient reported symptoms serve to explain the relationship between perceived stress and a patient’s report of overall impact of fibromyalgia on day-to-day living.