Case Report
Lipid Emulsion as First Line Treatment in Ropivacain Induced Neurologic Toxicity
Evans Marc S* and Fournier Roxane | |
Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Switzerland | |
Corresponding Author : | Evans Marc S, MD Department of Anesthesiology Pharmacology and Intensive Care University Hospitals of Geneva, Switzerland Tel: +41223823311 E-mail: marc.evans@hcuge.ch |
Received December 06, 2012; Accepted March 30, 2012; Published April 14, 2012 | |
Citation: Evans Marc S, Roxane F (2012) Lipid Emulsion as First Line Treatment in Ropivacain Induced Neurologic Toxicity. J Pain Relief 1:107. doi: 10.4172/2167-0846.1000107 | |
Copyright: © 2012 Evans Marc S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
Abstract
A 67 year old female patient presented with new neurological deficits (clonic movements, progressive confusion, dysarthria) and hemodynamic instability (hypotension, sinus tachycardia) immediately after uneventful performance of a sciatic block. Prompt infusion of a 100 ml intralipid emulsion in addition to a single bolus of 100 mcg phenylephrine reversed these signs within less than five minutes. Subsequently she remained hemodynamically stable and her neurological status returned to baseline. In absence of further signs of toxicity, the continuous intralipid infusion was interrupted.