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ISSN: 2168-9652

Biochemistry & Physiology: Open Access
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Review Article

Methods of Rapid Microbiological Assay and Their Application to Pharmaceutical and Medical Device Fabrication

Hideharu Shintani*
Faculty of Science and Engineering, Chuo University, Tokyo, Japan
*Corresponding Author : Hideharu Shintani
Faculty of Science and Engineering, Chuo University
1-13-27, Kasuga, Bunkyo, 112-8551, Tokyo, Japan
Tel: +81425922336
Fax: +81425922336
E-mail: [email protected]
Received August 13, 2014; Accepted August 13, 2014; Published August 29, 2014
Citation: Shintani H (2014) Methods of Rapid Microbiological Assay and Their Application to Pharmaceutical and Medical Device Fabrication. Biochem Physiol 3:141. doi:10.4172/2168-9652.1000141
Copyright: © 2014 Shintani H. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

There are several well-developed rapid microbiological methods now becoming available that may have useful applications in pharmaceutical and medical devices. They are ATP bioluminescence, fluorescent labeling, electrical resistance, and nucleic acid probes. In choosing to employ rapid methods, the microbiologist should examine their prospective performances against the specific requirements for that sector. Some methods may require expensive equipment and offer full automation, and others represent only a small investment. The regulatory view of these methods is changing and they still officially have not been approved in medical and pharmaceutical area, but it will still be up to the microbiologist to demonstrate that the method chosen is fit for the purpose intended.

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