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Motor Cortex Stimulation for Chronic Central and Peripheral Neuropathic Pain: State of Art

Guzzi Giusy1, Della Torre Attilio3, Colica Carmen2, Lavano Serena Marianna3, Giuseppe Vescio3, Volpentesta Giorgio3 and Lavano Angelo1,*
1Unit of Functional Neurosurgery, Department of Medical and Surgery Sciences, University “Magna Graecia”, Catanzaro, Italy
2Institute of Bio imaging and Molecular Physiology (IBFM), National Research Council, Catanzaro, Italy
3Doctorate in Life Sciences, Department of Health Sciences, University “Magna Graecia”, Catanzaro, Italy
Corresponding Author : Lavano A
Full Professor, Unit of Functional Neurosurgery
Department of Medical and Surgery Sciences
University “Magna Graecia”, Catanzaro, Italy
Tel: +399613647385
E-mail: lavano@unicz.it
Received: October 30, 2015 Accepted: December 02, 2015 Published: December 04, 2015
Citation: Giusy G, Attilio DT, Carmen C, Marianna LS, Vescio G, et al. (2015) Motor Cortex Stimulation for Chronic Central and Peripheral Neuropathic Pain: State of Art. J Pain Relief 4:219. doi:10.4172/2187-0846.1000219
Copyright: © 2015 Giusy G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Motor cortex stimulation (MCS) was proposed by Tsubokawa in 1991 for the treatment of post-stroke thalamic pain. Since that time, the indications enlarged including trigeminal neuropathic pain and other types of central and peripheral deafferentation pain. Clinical knowledge of MCS derives mainly from published individual cases and case series. Mechanisms underlying the effects of MCS are not yet clearly known. Empirical approach is generally used to select the optimal parameters by adjusting the combination of contacts, polarity, frequency, pulse width and amplitude, according to the patient’s pain relief. Complications are relatively rare but long-term loss of efficacy is reported.

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