Sleep Disorders in Fibromyalgia Syndrome | OMICS International | Abstract
ISSN: 2167-0846

Journal of Pain & Relief
Open Access

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Review Article

Sleep Disorders in Fibromyalgia Syndrome

Maurizio Rizzi1*, Andrea Cristiano1, Francesca Frassanito1, Claudio Macaluso1, Andrea Airoldi1 and Piercarlo Sarzi-Puttini2
1Respiratory Unit, Center for Sleep and Respiratory Disorders “Luigi Sacco” University Hospital, Milan, Italy
2Rheumatology Unit, “Luigi Sacco” University Hospital, Milan, Italy
*Corresponding Author : Maurizio Rizzi
Ospedale “Luigi Sacco” Azienda Ospedaliera
Polo Universitario, Via GB Grassi, 74, 20157, Milano, Italy
Tel: 390239042277
Fax: 390239042613
E-mail: [email protected]
Received: January 22, 2016; Accepted: February 08, 2016; Published: February 10, 2016
Citation: Rizzi M, Cristiano A, Frassanito F, Macaluso C, Airoldi A (2016) Sleep Disorders in Fibromyalgia Syndrome. J Pain Relief 5:232. doi:10.4172/2167-0846.1000232
Copyright: © 2016 Rizzi M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Chronic pain in patients affected by fibromyalgia is nowadays considered as a result of dysregulated mechanisms in the central nervous system. As fibromyalgia patients often report sleep disturbances, some researches have investigated potential central neural dysfunctions which link chronic pain and alterations responsible for sleep disorders. Polysomnography in fibromyalgia patients reveals increased EEG alpha activity during non REM sleep, increased number of arousal and a more frequent occurrence of cyclic alternating pattern. Mechanisms potentially linking chronic widespread pain to sleep alterations and mood disorders have not been proved. The relationship between polysomnographic findings and clinical symptoms in patients with fibromyalgia supports the hypothesis of a conceptual common mechanism called central sensation. The first step in the therapeutic approach is sleep assessment, including sleep history, identification of factors interfering with sleep hygiene and the diagnosis of any underlying disorder that may affect sleep. Food and Drug Administration has approved drugs for fibromyalgia that can improve sleep quality, but not specific for treatment of fibromyalgia associated sleep disorders. Both pharmacological and non pharmacological treatments should be used cautiously in fibromyalgia patients, considering underlying disorders and their potential interactions. However they could be an effective treatment both for fibromyalgia related pain and coexisting sleep alteration.