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Treatment of Medial and Lateral Elbow Tendinosis with an Injectable Amniotic Membrane Allograft a retrospective case series
| Danielle Aufiero1*, Steven Sampson2, Kentaro Onishi3 and Angie Botto-van Bemden4 | |
| 1The Orthohealing Center, Los Angeles, CA; David Geffen School of Medicine at UCLA, Los Angeles, CA; Western University of Health Sciences, Pomona CA; Touro University California, Vallejo, CA. | |
| 2The Orthohealing Center and The Orthobiologic Institute (TOBI), David Geffen School of Medicine at University of California Los Angeles, CA; 10780 Santa Monica Blvd, Suite 440, Los Angeles, CA 90025 Western University of Health Sciences, Pomona CA; Touro University California and Touro University New York, NY. | |
| 3The Orthohealing Center, Los Angeles, CA; University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania- Assistant Professor; Department of Physical Medicine & Rehabilitation and Assistant Director of Sports Medicine Fellowship. | |
| 4Musculoskeletal Research International (MRI) and Clinical Research Experts (CRE) Fort Lauderdale, FL; Florida International University, Miami. | |
| *Corresponding Author : | Danielle Aufiero Musculoskeletal Research International (MRI) and Clinical Research Experts (CRE) Florida International University, Miami, 1004 Avocado Isle, Ft. Lauderdale FL 33315, Florida Tel: 954-763-2670 E-mail: avanbemden@hotmail.com |
| Received: January 02, 2016 Accepted: April 12, 2016 Published: April 15, 2016 | |
| Citation: Aufiero D, Sampson S, Onishi K, Bemden VAB (2016) Treatment of Medial and Lateral Elbow Tendinosis with an Injectable Amniotic Membrane Allograft – A Retrospective Case Series. J Pain Relief 5:242. doi:10.4172/2167-0846.1000242 | |
| Copyright: © 2016 Aufiero D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | |
Abstract
1.1 Background: Epicondylitis is the second most frequently encountered head and upper limb musculoskeletal diagnosis in primary care clinics, with an incidence rate as high as 7/1,000 patients per year. Chronic or recalcitrant epicondylitis- more appropriately termed epicondylosis or elbow tendinosis- is not uncommon and represents a notable set of pathologies which account for lost recreation time, decreased quality of life, and workers compensation claims. A novel non-operative option has recently become available in the form of micronized dehydrated human amniotic/chorionic membrane (mDHACM) allograft. 1.2 Hypothesis: mDHACM allograft is known to be rich in anti-inflammatory cytokines and tissue inhibitors of metalloproteinase and IL-10. It also contains an abundance of growth factors and cytokines. In vivo and in vitro studies have shown reduction in scar tissue. We hypothesize that mDHACM allograft will be a viable treatment option in patients with epicondylosis. 1.3 Study design: Retrospective case series 1.4 Level of evidence: IV 1.5 Methods: Charts were retrospectively reviewed for 10 patients who received mDHACM allograft injections for treatment of medial or lateral epicondylosis.
