alexa Antibiotic-impregnated Central Venous Catheters For The Prevention Of Catheter-related Bloodstream Infection In Children: A Meta-analysis
ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

4th International Congress on Infectious Diseases
May 11-12, 2017 Barcelona, Spain

Vaneza Leah A Espino, Melissa A Dator and Maria Liza Antoinette M Gonzales
UP-Philippine General Hospital, Philippines
ScientificTracks Abstracts: J Infect Dis Ther
DOI: 10.4172/2332-0877-C1-023
Abstract
Background: Use of central venous catheters (CVCs) ensures stable access in critically ill patients but is associated with increased infection rates. CVC with antimicrobials has been recommended for infection reduction in adults. A review of antibiotic-impregnated CVCs’ usefulness in children is needed. Aim: Aim of this study is to determine the effectiveness of antibiotic-impregnated CVCs in reducing infection in children. Search Methods: Extensive search of MEDLINE, Cochrane Database of Systematic Reviews and Cochrane Register of Controlled Trials, Clinicaltrials.gov and Google scholar was done for trials published until June 2016. Reference lists from retrieved journals were checked for relevant articles. Selection Criteria: RCTs evaluating antibiotic-impregnated was compared with standard CVCs for reducing infection in children. Data Collection and Analysis: Two authors assessed trial quality and extracted data. Statistical analysis was done using Review Manager with fixed or random effects model. Outcomes were: Bloodstream infection, hypersensitivity, thrombosis, mortality, site infection, length of ICU and hospital stay. Dichotomous data were presented as risk ratios (RR), continuous data as mean differences with 95% confidence intervals (CIs). Results: Two low quality trials (n=1773) were analyzed showing non-significant reduction of bloodstream infection in the antibioticimpregnated group compared to standard catheters (RR 0.49; 95% CI 0.23-1.02, I2=0%) with no increased risk of thrombosis (RR 1.04 95% CI 0.84-1.28, I2=0%). No statistical difference was seen in the duration of ICU and hospital stay. Conclusions: The use of antibiotic-impregnated CVCs cannot be recommended at this time. Decision of its use will depend on the clinical judgment after consideration of the costs and benefits. More RCTs are needed to reinforce the evidence.
Biography

Vaneza Leah Espino is a pediatrician who recently completed her 3-year residency training at the Philippine General Hospital (PGH), one of the premier training institutions in the Philippines, and plans to pursue further training in Pediatric Intensive Care. The PGH caters to a large volume of patients from all parts of the country with illnesses ranging from the most common to the rarest and complicated. This challenge is often faced by being a resourceful, disciplined and efficient health care provider. Her training has molded her to be in a continuous pursuit to provide premium health care for every Filipino child despite limitations in resources. The review aims to provide evidence to decrease infection rates in the critically ill and to provide a spring board towards the development of similar trials for the pediatric population that may offer recommendations to be implemented in tertiary hospitals of developing countries.

Email: vielespino@gmail.com

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version