alexa Anticariogenic Properties Of Certain Naturally Occurring Polyphenols Targeting Streptococcus Mutans
ISSN: 2155-952X

Journal of Biotechnology & Biomaterials
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

6th World Congress on Biotechnology
October 05-07, 2015 New Delhi, India

Dimple Goyal, Sukesh Sharma and Akhtar Mahmood
Panjab University, India
Posters-Accepted Abstracts: J Biotechnol Biomater
DOI: 10.4172/2155-952X.C1.044
Abstract
The role of S. mutans in the pathogenesis of dental caries among human populations is well established. To prevent and control the disease, it is imperative to look for new, safe and effective compounds. In this study, we have investigated the effect of naturally occurring polyphenols viz., Gallic, tannic, syringic acids and catechins on certain cariogenic activities of S. mutans. The polyphenols inhibited the activities of dextran sucrase (44-89%) and glycosylt ransferase (27-36%), key enzymes of sucrose metabolism in S. mutans. The growth of S. mutans was also impaired by polyphenols in vitro, which yielded MIC of the order of 136 (gallic acid), 50.5 (tannic acid) and 510 (Syringic acid) μg/ml, respectively. The polyphenols reduced biofilm formation, hydrophobicity and acid production by the organism under in vitro conditions. Tannic and Gallic acids were more effective in inhibiting the bacterial growth compared to syringic acid or catechins. Flourescence microscopy revealed that in the absence of polyphenols, the cells were present as clumps however; they were well separated in presence of gallic acid (68 μg per ml) or tannic acid (25.5 μg/ml), due to the inhibition of biofilm formation. The present data suggests cariostatic action of Gallic, syringic and tannic acids in S. mutans which may have potential use in the prevention and cure of dental caries.
Biography

Dimple Goyal has completed her Master’s in Biochemistry from Panjab University. She is currently pursuing her PhD in Biochemistry on topic entitled as “Studies on the interaction of plant polyphenols with dextransucrase activity in Streptococcus mutans: Anticariogenic perspective”. She has published two publications in international peer review journals. She is the recipient of Research Fellowship from University Grants Commission, New Delhi.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version