Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar


Application Of Process Analytical Technology (PAT) For Bioprocess Production Environment | 8507
ISSN: 2155-952X

Journal of Biotechnology & Biomaterials
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Recommended Conferences

29th Asia Pacific Biotechnology Congress

Dubai, UAE
Google Scholar citation report
Citations : 2154

Journal of Biotechnology & Biomaterials received 2154 citations as per Google Scholar report

Indexed In
  • Index Copernicus
  • Google Scholar
  • Sherpa Romeo
  • Open J Gate
  • Genamics JournalSeek
  • Academic Keys
  • ResearchBible
  • China National Knowledge Infrastructure (CNKI)
  • Access to Global Online Research in Agriculture (AGORA)
  • Electronic Journals Library
  • RefSeek
  • Hamdard University
  • OCLC- WorldCat
  • SWB online catalog
  • Virtual Library of Biology (vifabio)
  • Publons
  • Geneva Foundation for Medical Education and Research
  • Euro Pub
Recommended Journals
Share This Page

Application of process analytical technology (PAT) for bioprocess production environment

World Congress on Biotechnology

Sreenivasula Reddy Ramireddy

ScientificTracks Abstracts: J Biotechnol Biomaterial

DOI: 10.4172/2155-952X.1000001

As defined by US FDA, Process Analytical Technology (PAT) is a system for designing, analyzing, and controlling manufacturing through timely measurements of critical quality and performance attributes of raw and in-process materials and processes with the goal of ensuring final product quality. PAT helps in building quality in the products, reduce failures, cut down overall cost and time, and can also be a substitute for expert human resource. Its significance is highly pronounced in the production of high value recombinant healthcare products that go for human consumption because of stringent regulations of FDA. In R & D and production facilities for biotechnology products, PAT requirements include real time measurement of key process variables such as pH, DO, substrate concentration, production concentration, cell growth, cell broth viscosity, off-gas composition, and concentration of harmful byproducts. In process analysis of typical physical and chemical parameters has been well established and is commonly used in lab scale, but not in production scale. Online measurement of key biological variables such as protein concentration is still a complex task at all scales. NIR, Raman Spectroscopy, fluorescence, dielectric based on-line, off-line and at-line systems in combination with expert system applications have filled the gaps to certain extent. Need for simple, robust, cheaper technologies for production facilities requires further research. A few case studies of Pichia pastoris, E. coli and Saccharomyces fermentations are presented to demonstrate the application of PAT for production of high value recombinant healthcare products.
Dr. Sreenivasula Reddy Ramireddy has completed his Ph.D. in Biochemical Engineering from University of Nebraska-Lincoln, USA. During and after his doctoral program, worked on more than 20 high value healthcare recombinant products in various bacterial and yeast expression systems. He participated in more than 500 fermentation processes in various scales mostly towards fermentation process development. He served more than 20 international clients including but not limited to US Armay/NIH/NIAID, Novartis, Proteon, Syngenta while working at BPDF, UNL and also as consultant. He founded two businesses one in USA and one in India, namely BioPATS and S4BIO. He developed one software product for control of bioreactor, BioPATS and a shake bioreactor. Several research and training projects/products are in progress. Earlier he worked as manager for fermentation development laboratory, BPDF, UNL, USA and also as guest faculty for bioprocess engineering and Technology at University of Hyderabad, India. His current clients include SRIBIOTECH, Hyderabad.