Journal of Infectious Diseases & Therapy
Open Access

Abstract

Background: Urinary and vaginal infectious diseases reached at high rate, issues of emerging and re-emerging infections due to drugresistant bacteria becomes a serious danger to human health, medicinal plants constitute a reservoir of bioactive molecules that can kill multidrug resistant microbial infection. In the context of this research, study was intended to characterize molecules bioactive of essential oil and its potentials against urinary and vaginal infections. Methods: The potential antimicrobial was characterized in vitro against 12 reference and clinical multi drug resistant strain encountered in clinical laboratory and the microbiology laboratory of Saidal Medea, Algeria. The minimum inhibitory concentrations (MIC) and the minimum microbicidal concentration (MMC) were determined by disc diffusion assay and agar dilution assay; GC/MS and CPG were utilized to detect the content of bioactive molecule of essential oil. Results: All strains was appeared sensitive to essential oil of Lavandula angustifolia Mill, minimum concentration value was 0.001 v/v can inhibit growth and kill E. coli ATCC1536 and Citrobacter braakii and Micrococcus luteus and Bacillus subtilis ATCC6133, C. albicans and C. albicans ATCC1231. Essential oil presented a good potential biostatic/biocidal. Lavandula angustofolai Mill was extremely higher against almost all microbes tested. The composition of bioactive molecule of essential oil was characterized as 45 components made up principally of linalyl anthranilate (31.92%) and linalool (25.63%). Conclusion: Lavender essential oil possesses strong potential microbicide against the bacterial and fungal human pathogens strains, it can consider as an alternative treatments.

Biography

Email: boudja.hadjira@yahoo.fr