Cholesterol Derivatives As Antimicrobial Agents | 4808
ISSN: 2155-952X

Journal of Biotechnology & Biomaterials
Open Access

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Cholesterol derivatives as antimicrobial agents

3rd World Congress on Biotechnology

Ashraf Mashrai, Shamsuzzaman, Hena Khanam, Anis Ahmad and Himanshu Gupta

ScientificTracks Abstracts: J Biotechnol Biomater

DOI: 10.4172/2155-952X.S1.009

Pathogen infections have threatened human?s health for thousands years. During past decades, with the abuse of antimicrobial agents, more and more drug-resistant pathogens were found. Among them, methicillin-resistant Staphylococcus aureus (MRSA) is a prominent pathogen, which causes a public health concern worldwide and associates with a high mortality. Novel antimicrobial agents against MRSA have been introduced recently. However, the emergency of resistance and side effects for those agents raise the need for novel antimicrobial agents. In this work, a series of Cholesterol derivatives were checked for their antimicrobial activity, insilico metabolism, toxicity prediction, exploration of new therapeutic potential, QSAR modeling of rat acute toxicity.