Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Diagnostic value of contrast-enhanced ultrasound for the differentiation of breast lesions: A metaanalysis

3rd International Conference on Radiology and Imaging

Xuelei Ma1, Rongjun Liu1, Jing Zhang1, Jinna Chen2, Feng Yang2 and Hongyuan Jia1

1West China Hospital of Sichuan University, PR China 2Sichuan University, PR China

Posters-Accepted Abstracts: OMICS J Radiol

DOI: 10.4172/2167-7964.S1.007

Abstract
The objective of this study was to systematically review and evaluate the diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in differential diagnosis of benign and malignant breast lesions. The scientific literature databases PubMed and Embase were comprehensively searched for relevant studies before January 2015. Data were pooled to yield summary sensitivity, specificity, positive likelihood ratios (PLR), negative likelihood ratios (NLR), and diagnostic odds ratio (DOR) using Meta-Disc Version 1.4 software. A total of 31 studies with 2395 lesions were considering eligible following predefined criteria. The pooled sensitivity, specificity and DOR was 0.88 (95% CI, 0.86-0.90) and 0.80 (95% CI, 0.78-0.82), respectively. The pooled positive and negative likelihood radios was 4.18 (95% CI, 3.01-5.80), and 0.16 (95% CI, 0.11-0.24), respectively. The pooled DOR of was 30.36 (95% CI, 16.41-56.14) and the area under the curve (AUC) of SROC was 0.9136 (standard error: 0.0226). In the subgroup analysis, the pooled results of real time gray scale or harmonic modality with second generation contrast agents groups were significant better than other groups. All subgroup analysis did not diminish the heterogeneity due to variability in study factors. There was no significant publication bias according to Deeks��? funnel plot asymmetry test. In conclusion, the comprehensive results suggested that CEUS could be a potential reliable method for differential diagnosis of benign and malignant breast lesions, the second generation contrast agents increase diagnostic accuracy of CEUS and real time gray scale and harmonic modality could be more suitable to perform CEUS.
Biography

Email: drmaxuelei@gmail.com

Top