Enhancement Of Cosmeceutical Activities Of Codonopsis Lanceolata By Steaming Process | 12203
ISSN: 2155-952X

Journal of Biotechnology & Biomaterials
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Enhancement of cosmeceutical activities of Codonopsis lanceolata by steaming process

4th World Congress on Biotechnology

Woo Seok Choi, Ji Seon Kim, Choon Je Ma, Jae Youn Chung, Hee Chu Chung and Hyeon Yong Lee

Posters: J Biotechnol Biomater

DOI: 10.4172/2155-952X.S1.024

This study were performed to the cosmeceutical activities of compare to steamed Codonopsis lanceolata and just Codonopsis laceolata: Codonopsis lanceolata extracted by 70% ethanol extraction at 60 (SCE1), extracts of three-times steaming process and 70% ethanol extraction at 60 (SCE3), extracts of five-times steaming process and 70% ethanol extraction at 60 (SCE5) and extracts by 70% ethanol extraction at 60 (CE),.The highest extraction yield was measured as 25.2% for extracts of five-times steaming process, whose value was very close to 24.4% from once steaming process .DPPH free radical scavenging activity of the extracts from five-times steaming process showed high ratio as 74.68%,followed by 52.02, 61.42 and 63.34(%) from ethanol extraction at 60 (CE), extracts of once steaming process and 70% ethanol extraction at 60 (SCE1), extracts of three-times steaming process and 70% ethanol extraction at 60 (SCE3), respectively. The lowest cytotoxicity against from fibroblast cell line, CCD-986sk was observed in adding 1 mg/mL of the extracts from five-times steaming process. The extracts from both five-times steaming process and ethyl alcohol extraction effectively reduced the expression of MMP-1 on UV-irradiated human fibroblast CCD-986sk cells as 44.3% and was showed hightyrosinase inhibitory potency as 66.8%. The other extracts show relatively low activities in the range of 36~54(%). From these results, we concluded that the extracts of Codonopsis lanceolata could be used for anti-aging and skin-whitening agent, and extracts from five-times steaming process should be a more efficient process than 70% ethanol extraction.
Woo Seok Choi attends the Department of Medical Biomaterials Engineering in Kangwon National University, Korea and he will graduate from in 2014. Now he is a student in Food & Bioprocess Engineering Lab in Kangwon National University and he apply for admission to the master?s course in Kangwon National University.