Journal of Biotechnology & Biomaterials
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Fundaci?n medina?s collections: Integrated solutionfor natural products HTS drug discovery
5th World Congress on Biotechnology
J R Tormo, C Moreno, F Mu?oz, V Gonz?lez-Men?ndez, I Gonz?lez, D Oves, JPascual, R Luque, G Platas, M Est?vez, J Mart?n, N El Aouad, I P?rez-Victoria, G
Crespo, M de la Cruz, C Diaz, N de Pedro, L Rodriguez, A Melguizo, F Vicente, F Reyes and O Genilloud
Based on more than fifty years of cumulative experience in the pharmaceutical industry and with international
collaborations, Fundaci?n MEDINA continues creating, improving and characterizing a high quality Natural Product
Extract Collection for HTS Drug Discovery. This precious resource is open to worldwide discovery initiatives focused on novel
therapeutic approaches and the clinical development of medicinal agents.Fundaci?n MEDINA offers the scientific community
an integrated solution for Natural Product Drug Discovery derived from a superbly diverse, laboratory-optimized and well-
maintained microbiological arsenal resulting in a collection thoroughly annotated with chemical data. Fundaci?n Medina?s
Natural Product Collections contain more than 120,000 extracts and cover an uncommonly unexplored broad chemical space
resulting from a variety of fermentation products. The extensive characterization of their diverse microbial sources, the creation
of specific modules enriched in antimicrobial activities, the use of innovative semi-automated methodologies for extraction
and fractionation, as well as the characterization of their chemical diversities by mass spectrometry profiling, allows us to offer
with these Collections, a superb source of potential new candidates for HTS Drug Discovery.
J R Tormo is Associate Area Head of Chemistry & Collection Manager at Fundaci?n MEDINA, where he is leading the creation and management of the microbial
and plants Natural Products Libraries and coordinates different Research Projects for Drug Discovery for new anti-infectives. Finished his PhD studies in the Faculty
of Pharmacy of the University of Valencia in 2000, presents more than fifteen years of cumulative R&D experience including the management of multidisciplinary
teams in international (Research Fellow at Merck & Co) and Spanish (R&D Director at ValentiaBioPharma) Biotech and Pharma companies.
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