High-resolution Transcript Profiling Of The Atypical Biotrophic Interaction Between Theobroma Cacao And The Fungal Pathogen Moniliophthora Perniciosa | 12197
Journal of Biotechnology & Biomaterials
Like us on:
Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
High-resolution transcript profiling of the atypical biotrophic interaction between Theobroma cacao and the fungal pathogen Moniliophthora perniciosa
4th World Congress on Biotechnology
Daniela Paula de Toledo Thomazella, Paulo Jose Pereira Lima Teixeira, Osvaldo Reis, Paula Favoretti Vital do Prado, Maria Carolina
Scatolin do Rio, Gustavo Gilson Lacerda Costa, Ramon Oliveira Vida, Jorge Maur?cio Costa Mondego, Piotr Mieczkowski and
Goncalo Amarante Guimaraes Pereira
Witches broom disease (WBD), caused by the hemibiotrophic fungus Moniliophthora perniciosa, is one of the most devastating
diseases of Theobroma cacao, the chocolate tree. In contrast to other hemibiotrophic interactions, the WBD biotrophic
stage lasts for months and is responsible for the most distinctive symptoms of the disease, which comprise drastic morphological
changes in the infected shoots. Here, we used the dual RNA-seq approach to simultaneously assess the transcriptomes of
cacao and M. perniciosa during their peculiar biotrophic interaction. Infection with M. perniciosa triggers massive metabolic
reprogramming in the diseased tissues. Although apparently vigorous, the infected shoots are energetically expensive structures
characterized by the induction of ineffective defense responses and by a clear carbon deprivation signature. Remarkably, the
infection culminates in the establishment of a senescence process in the host, which signals the end of the WBD biotrophic stage.
Thus, M. perniciosa biotrophic mycelia develop as long-term parasites that orchestrate changes in plant metabolism to increase
the availability of soluble nutrients before plant death. Collectively, our results provide unprecedented findings on an intriguing
tropical disease and advance our understanding of the development of biotrophic plant-pathogen interactions.
Daniela Paula de Toledo Thomazella started her Ph.D. in the Brazilian graduate course in Genetics. Her work resulted in a high quality manuscript,
published in the journal New Phytologist (10.1111/j.1469-8137.2012.04119.x). Also, this study resulted in a patent application and was divulgated
by several Brazilian newspapers and by the prestigious newspaper Financial Times. Currently, Daniela is a postdoctoral researcher in Genetics and
Molecular Biology at the State University of Campinas (Brazil). Her research project focuses on comparative genomics and transcriptomics of the
Moniliophthora pathogens of cacao with the goal of understanding the molecular basis of their peculiar biology and infective strategies.
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals