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Marvin W Makinen
The University of Chicago, USA
Keynote: J Biotechnol Biomater
Marvin W. Makinen is Professor in the Department of Biochemistry and Molecular Biology in The University of Chicago, USA and has served as chairman of the department from 1988 to 1993. He is also a founding member of the Human Rights Board at the university. He did his D.Phil., in the year 1976 in Molecular Biophysics at Oxford University, U.K. Over the past 40 years at The University of Chicago, research in the Makinen lab has been directed towards the structural basis of action of metalloenzymes and the application of magnetic resonance methods to characterize active site structure and stereochemical relationships of substrates to active site residues in true reaction intermediates. More recent studies have been carried out to identify the target enzymes of metal -chelates that enhance the cellular uptake of glucose. Because some metal-chelates are associated with the capacity to enhance preferential uptake of glucose into xenograft tumors in small laboratory animal models, present research has been directed towards testing their potential as pharmacologic reagents to increase sensitivity of detection of malignant lesions by PET imaging.
Email: [email protected]
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