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|J Lodewyk F Kock|
|Key Note Forum: J Microbial Biochem Technol|
|This Keynote explores the ability of our Nano3A system to screen anti-mitochondrial antifungal, anticancer and anti-malarial drugs. Th is system consists of the Anti-mitochondrial Antifungal Assay (3A) linked to Nano Scanning Auger Microscopy (NanoSAM) and Nano Focused Ion Beam Time-of-Flight SIMS (NanoFIB-TOF) nanotechnologies. Here yeast sexual cells serve as indicators to screen drugs with anti-mitochondrial activity (3A system) while NanoSAM and NanoFIB-TOF are used to determine the drug’s metabolic fate as well as eff ects on sexual cell 3D ultrastructure and chemical composition as etching proceeds in nanometre slices through cell.|
Professor Lodewyk Kock is regarded as an internationally acclaimed researcher. He published 150 articles in reputed journals and was involved in many interviews on national radio, television as well as Voice of America and Reuters TV. He was appointed as Director: Industrial Biotechnology UNESCO MIRCEN since 1998 and is at present Commissioner of the International Commission on Yeasts (ICY). He received the President’s Award for outstanding research from the National Research Foundation. Professor Lodewyk Kock (PhD) and Dr. Chantel Swart (PhD; Co-author) are from the Department of Microbial, Biochemical and Food Biotechnology from the University of the Free State in South Africa.
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