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Wound infections often cause harmful and costly clinical complications to our health care systems. Infected wounds impose a
significantly negative effect on patient care and recovery as infection hinders wound healing, resulting in increased patient
morbidity and mortality. We screened 212 wound specimens from patients in some health institution in Buea municipality and
analyzed for common bacteria pathogens using standard microbiological and biochemical methods. Antimicrobial susceptibility of
isolates was determined using the disc diffusion assay. A total of 169 (79.9%) samples were infected. The frequencies of isolation from
various sources were as follows; burns 100%, ulcers 86.7%, post-operative wounds 79.3% and open wounds 78.8%. 12 bacterial species
were identified; Staphylococcus aureus, Escherichia coli, Enterobacter cloacae, Enterobacter aerogenes, Proteus mirabilis, Klebsiella
pneumoniae. Hafnia alvei, Pseudomonas aeruginosa, Serratia marcescens, Serratia rubideae, Serratia sakazakii and Streptococcus
sp. Results of antibiotic sensitivity tests revealed the most active drugs against these infectious agents to be ofloxacin (100%) and
perfloxacin (100%), followed by ceftriaxone (94.2%) and gentamicin (92%). Isolate exhibited complete resistance to oxacillin (100%).
Multi-drug resistance (resistance to five or more drugs) was exhibited by over 71.7% of isolates. Multi-drug resistance was commonly
encountered in Staphylococcus aureus with 31.5% of this organism being resistant to seven drugs.
Nde Godlove Tsi is currently a Second Year Student at the Faculty of Health Sciences with a Major in Medicine at the University of Buea – Cameroon.
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