Journal of Biotechnology & Biomaterials
Open Access

Abstract

Organ transplantation and its techniques have encountered a great deal of improvement and development in last 50 years after the first renal transplant which took place in 1950 in United States of America on Ruth tucker a 44 years women. Organ transplant have become safer and lesser risky due to several advancements in the surgical and medicinal fields. Renal transplant is one of the major organ transplant which accounts for around 12,000 transplants all over the world. Despite of these enhancements still there are failures and lives are lost due to low graft survival in the long run which is termed as chronic renal failure. This is also affected by lifestyle issues but mainly immunological and non immunological aspects like medication used, blood pressure, donor age, senescence and aging of the cells, late antibody response etc. Generally the age of the transplant and the patient is 8-12 years after the transplant takes place but the number of years that the patient lives can be increased and the life expectancy rate can be enhanced by the application of medication including Tacrolimus and cyclosporine and rapamycin etc and keeping a check on after transplant complications like increase in protein urea, development of antibodies in renal cells which can be detected by processes like ELISPOT etc. This way a longer and better life can be given to patients who have given so much in combating the disease.

Biography

Chirag Mohan Sharma is currently pursuing BSc in Medical Biotechnology from Amity Institute of Biotechnology, Amity University, India. He has an utter curiosity in the field of human physiology and response of human body to different drugs and he aspires to pursue masters in the same field.

Email: chiragmohansharma@gmail.com