Synthesis Of Novel Dendritic Macromolecules And Investigation Of Glucose Oxidase Enzyme As Biocatalysts | 17186
Journal of Biotechnology & Biomaterials
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Recently, dendritic macromolecules have received significant attention because of their good stability and high chemical
reactivity. Dendrons are different from dendrimers. Even though symmetry of the molecule is broken, there is a focal
point.To research, dendron including functional groups synthesized for enzyme immobilization. To prepare such a dendron,
the melamine is reacted with dialdehydeand ferrocene aldehyde by means Schiff ?s condensation method and characterized via
1H-NMR, FT-IR and LC-MS. Immobilized Glucose Oxidase Enzyme (GOx) on to novel dendron showed two optimum pH.
The influence of reusability and storage capacity on the free and immobilized glucose oxidase enzyme was investigated. After
10 months, the immobilized enzyme (on studied dendron) retained 92.80 % of its original activity. High activitiy was found for
immobilized enzyme. This result suggests that the studied dendron-support confer a higher conformational stability upon the
immobilized enzyme due to form of covalent bond.
Elvan Hasanoğlu ?zkan received maximum score her bachelor?s degree from Niğde University in chemistry in 2007. In 2009, she received her Master?s degree in
Inorganic Chemistry from Universty of Niğde. She is currently working on a PhD degree at Gazi University under the direction of Associate Professor Dr. Nurşen
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