Journal of Radiology
Open Access

Abstract

The presentation will address blood and imaging biomarkers in mild traumatic brain injury and studies led by Dr. Shetty at the Hospital for Special Surgery. The GE-NFL Advanced MRI Applications/Abbot Biomarker Candidates for mTBI study is an analysis of investigational MR imaging and blood biomarker identification in subjects who have recently sustained a concussion. The specialized MRI software is correlated with detailed neurological assessments and 11 brain-tissue specific blood biomarkers that are expected to peak and then normalize following a concussion. Presently, 44 subjects are enrolled in the imaging portion with 42 subjects co-enrolled in the blood biomarker portion. 20 subjects have been enrolled in both imaging and blood biomarker at encounter 1 (within 72 hours of injury). 86 subjects were enrolled between March 2014 and June 2015 with 26 healthy controls matched for age, gender, handedness, level of education and socioeconomic status

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