Clinical Pharmacology & Biopharmaceutics
Open Access

Daniel R Lewis

New Products Research and Development, GlaxoSmithKline, Parsippany, NJ, USA

Biography

Dr. Lewis serves as the President and Chairman of the board of OrthoCarolina. He is the member of American Society for Surgery of the Hand (ASSH), American Academy of Orthopedic Surgeons (AAOS), American Association of Hand Surgeons (AAHS), North Carolina Orthopedic Association (NCOA) and Mecklenburg Medical Society. His research interests reflect in his wide range of publications in various national and international journals.

Publications

Direct Measurement of Lipase Inhibition by Orlistat Using a Dissolution Linked In Vitro Assay

Purpose: To develop a bio-assay that would be able to directly test gastrointestinal and/or dissolution samples to determine lipase activity and inhibition by Orlistat. Methods: Enzyme assays were performed with porcine pancreatic lipase and para-Nitrophenyl Palmitate (pNPP) in pH 8.0 reaction buffer at 37°C. Substrate hydrolysis was monitored... Read More»

Daniel R Lewis and Dongzhou J Liu

Research Article: Clin Pharmacol Biopharm 2012, 1:103

DOI: 10.4172/2167-065X.1000103

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF