Koji Shimoke | OMICS International
ISSN: 2167-065X

Clinical Pharmacology & Biopharmaceutics
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Koji Shimoke

Faculty of Chemistry, Materials, and Bioengineering and Strategic Research Base, 3-3-35, Yamate-cho, Suita, Osaka 564-8680

Mechanisms of Neurotrophic Activities via Low-molecular-weight Compounds: Post-transcriptional Regulation in PC12 Cells and Neurons

Recently, it was reported that some low-molecular-weight compounds mimic neurotrophic activities including neurite outgrowth and neuroprotection. Carnosic acid (CA) promotes neurite outgrowth through the activation of Nrf2 in a model of neuron PC12 cells. CA also protects neurons from oxidative stress via the keap/Nrf2 transcriptional pathway. Lute... Read More»

Hiroki Maruoka and Koji Shimoke

Review Article: Clin Pharmacol Biopharm 2013, S1: 003

DOI: 10.4172/2167-065X.S1-003

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF