Shinya Munakata | OMICS International
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
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Shinya Munakata

2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421

Pharmacological Targeting of Neutrophil Serine Proteases Prevents Lethality in Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice

Background and aims: In recent years the number of patients with inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis has been on the rise. Neutrophils are thought to be first cells to colonize disease-state colon tissue. Neutrophil elastase (NE) and cathepsin-G (Cat-G) are major secretory products from activated neutrop... Read More»

Hisashi Ro, Shinya Munakata, Takae Ueyama, Hiromitsu Komiyama, Makoto Takahashi, Yutaka Kojima, Yuichi Tomiki and Kazuhiro Sakamoto

Research Article: J Gastrointest Dig Syst 2018, 8: 551

DOI: 10.4172/2161-069X.1000551

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