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Dr. Angelica Merlot is a Postdoctoral Research Associate in the Pathology Department of the University of Sydney. She heads the Cancer Therapeutics Group within the Molecular Pharmacology and Pathology Program. During her PhD, she investigated the pharmacological mechanisms of action and membrane transport of anti-cancer thiosemicarbazones. The most potent agent of this class is entering clinical trials in 2016. Angelica is interested in improving the targeting and pharmacological complications of cancer therapies that cause toxicity and drug resistance. Her current research focuses on the characterization of the endoplasmic reticulum stress pathways in cancer and modulating these signals to induce cancer cell death and inhibit metastasis.
Oncology, Drug Delivery, Albumin, ER Stress, Endocytosis, Metastasis, Cell Biology, Membrane Transport, Cancer Cell Biology, Iron Metabolism, Chemotherapy, Molecular Biology.
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